Associate Scientist, Downstream Process Development
: Job Details :


Associate Scientist, Downstream Process Development

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Location: Gaithersburg,MD, USA

Date: 2024-12-12T13:18:52Z

Job Description:

Job Summary

We are seeking an Associate Scientist to join our Downstream Process Development group in Gaithersburg, MD. The role involves hands-on execution of downstream chromatography and filtration processes for process development, scale-up, process characterization, and technical support of cGMP manufacturing for proteins, nanoparticles, and VLP-based vaccines. The candidate will execute, analyze, and report experiments and draft technical development reports. This contract position has the potential to become permanent.

Essential Functions

  • Reproduce chromatography and filtration processes to support process development/characterization.
  • Complete scale-up runs and development reports to support technology transfer to manufacturing.
  • Maintain and monitor equipment, proposing modifications for process improvements.
  • Assist in implementing new technologies to enhance downstream purification processes.
  • Support technology transfer to Manufacturing and external partners, including training, equipment recommendations, and troubleshooting.
  • Generate, manage, and evaluate data and records for regulatory compliance.
  • Author technical reports, data summaries, and SOPs, and present findings at internal meetings.
  • Collaborate with colleagues to discuss data, draw conclusions, and design experiments.

Required Skills & Abilities

  • BS in Bio/Chem Engineering, Biology, Chemistry, Biochemistry, or related discipline with 3+ years of experience, or MS with 1+ year
  • Experience with small-scale insect/mammalian purification process development.
  • Practical experience with chromatography systems, filtration, and other biomanufacturing unit operations.
  • Experience with centrifugation and cell culture clarification is a plus.
  • Strong communication, troubleshooting, and record-keeping skills.
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