Clinical Research Associate
: Job Details :

Are you ready to join Connecticut Innovation's vibrant community of innovators? Connecticut Innovations (“CI”) is Connecticut's strategic venture capital arm, and we are passionate about serving our portfolio of 220+ companies across various industries, with strengths in life sciences, technology, and climate tech.

Come join Taking Hold. Conquering Cancer. - Halda TherapeuticsHalda Therapeutics as Research Associate!

Halda Therapeutics

Halda Therapeutics is a New Haven CT based, venture-backed biotechnology company focused on the development of a proprietary RIPTAC™ (Regulated Induced Proximity TArgeting Chimeras) therapeutic that works by a novel “hold and kill” mechanism for the precision treatment of cancer. The mechanism of action of RIPTAC therapeutics is uniquely designed to address cancer's ability to evolve bypass mechanisms of resistance, a common limitation of today's precision oncology medicines.

Our lead RIPTAC programs are in development for major solid tumor types, prostate cancer and breast cancer, with additional RIPTAC therapeutic programs in our pipeline to treat unmet medical needs in cancer. The company will initiate its Phase 1 trial in metastatic, castration-resistant prostate cancer (mCRPC) in 2025. Halda was founded by Yale Professor Craig Crews and is led by a team with deep expertise in bifunctional drug discovery, platform innovation, and company building and is located in New Haven, CT. The company has raised $202M in funding from top tier investors, and closed on $126M in the summer of 2024 to bring its first two programs into the clinic.

At Halda, our team is a collective force for drug innovation to conquer cancer. Halda is a place where you can embrace your purpose and be your true self. Learn more about us at www.haldatx.com.

Research Associate/Associate Scientist in Biology

Halda is seeking an industrious individual to join our growing Profiling Group within the Biology Department. The candidate will be responsible for assessing the activity of compounds using various cellular and biochemical assays. This position requires cross-disciplinary interactions with fellow biologists, medicinal chemists, and structural biologists as well as a willingness to learn new techniques in a fast-paced environment. The title for this position is commensurate with the candidate's experience and skill set. The position will be located at our headquarters at Science Park in New Haven, CT.

Key Responsibilities

• Design, develop and execute cell-based and biochemical assays to assess compound activity and mechanism of action
• Cell culture maintenance and cell line generation including transfections and transductions
• Analyze and interpret assay data to make recommendations for further experiments
• Document experimental work in our electronic lab notebook (LIMS)
• Generate timely, high-quality data and troubleshoot assays when necessary
• Contribute to scientific publications, poster presentations and patent applications
• Participate in lab management responsibilities as needed

Qualifications

• B.S. or M.S. degree with 0-5 years' experience in Industry setting
• Able to thrive in a multifunctional role at a nimble, fast-growing biotech
• Good interpersonal skills and willingness to work within a team to advance drug discovery projects
• Strong work ethic, responsibility, and positive work habits with the ability to prioritize tasks
• Attention to detail and time management skills within a fast-paced environment are absolutely essential
• Able to explain experimental design and results to the team in a clear and concise manner
• Able to teach team members new assay formats and techniques
• Familiarity with routine laboratory applications and ability to follow standard scientific techniques and methods to perform experiments at the bench
• Experience with cell culture, qPCR, Western blots, ELISAs, FRET assays, In-Cell Westerns and viability assays among other microplate-based assay formats is preferred
• Ability to use manual and electronic multichannel pipettors, liquid handling instrumentation and microplate readers is a plus
• Familiarity with Microsoft Office is required; experience with Graphpad Prism and LIMS is a plus

Compensation

The estimated salary range for this position is $70,000 to $100,000. Actual title and compensation will be dependent on candidate experience and other factors. Compensation will also include an annual bonus and equity.

Benefits

Halda offers a competitive benefit package, including vacation, subsidized medical, dental, vision, ST/LT disability, commuting, a 401k Plan with generous company contribution and free parking at our New Haven headquarters. We also offer tuition reimbursement and paid parental leave.

If you are interested in this opportunity and meet the requirements, please submit your resume and cover letter for consideration to ...@haldathera.com. Halda is an Equal Opportunity Employer.