We use science to save lives, and so can you.
We are looking to recruit a Director, Downstream Process Development to lead the Downstream Process Development function specialising in viral vector production.
The objective of the role is to develop, optimize, and scale downstream processes, guiding the team in delivering robust and efficient process development solutions to our clients. This Bedford, MA based position is an exciting opportunity to shape the strategic direction of Viral Vector downstream process development within a dynamic CDMO environment.
Your responsibilities in this role would be:
- Lead a team of Research Associates and Scientists in AAV downstream process development. Mentor, coach, and provide career development opportunities aligned with individual team members and company goals.
- Establish and implement strategies to enhance and continuously improve OXB's Downstream Process Development platform, ensuring delivery of efficient, scalable, and high-quality processes and products to clients.
- Partner closely with Upstream Process Development, Drug Product Development, Analytical Development, and other cross-functional teams to align on shared goals and priorities, optimizing the end-to-end development process while delivering on the pipeline. Provide technical support to cGMP manufacturing as needed.
- Serve as a key point of contact for clients, presenting technical data and updates to cross-functional stakeholders, both internally and externally. Cultivate strong relationships with client teams to support the success of their programs.
- Leverage expertise in Chemistry, Manufacturing, and Controls (CMC) to drive the development, scale-up, and tech transfer of AAV downstream processes. Ensure all processes meet quality and regulatory standards to support clinical and commercial production.
We are looking for:
- BS (12+), MS (10+) PhD (8+) years industry experience. Degree in microbiology, biochemistry, biotechnology, chemical engineering, or molecular biology.
- Hands-on experience in viral vector process development, scale-up, tech transfer, and manufacturing support.
- Experience in unit operations including clarification, capture and polishing chromatography, and UF/DF.
- Experience with downstream process development and characterization following QbD principles.
- Strong leadership and management skills, with the ability to effectively lead and motivate a team of scientists and research associates to work in a fast-paced, highly collaborative environment.
- Strong communication and presentation skills, with the ability to effectively convey technical information to cross-functional teams and external stakeholders.
- Able to effectively manage and prioritize multiple parallel activities including long-term vision and short-term deliverables.
- Independently motivated, highly organized, detail oriented and good problem-solving ability.
About Us:
OXB is a quality and innovation-led viral vector CDMO (Contract Development and Manufacturing Organization) with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.
OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus, and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise
What's in it for you:
- Competitive reward packages
- Development opportunities
- Welcoming, friendly, supportive colleagues
- A diverse and inclusive working environment
- State of the art laboratory and manufacturing facilities
We want you to feel inspired every day. We're future-focused and our business is growing rapidly. We succeed together through passion, commitment and teamwork, and so can you.
At OXB (US) LLC we are committed to providing equal opportunity to all employees and applicants.
Our policy is to recruit, hire, train, and reward employees for their individual abilities, achievements and experience without regard to race, color, religion, sexual orientation, age, national origin, disability, marital or military status.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.
Collaborate. Contribute. Change lives