ProQR Therapeutics is a biotechnology company listed on NASDAQ with offices in Leiden, the Netherlands and Cambridge, Massachusetts, USA. ProQR is focused on the development of life-changing RNA therapies to meet the unmet need of individuals and families with common and rare diseases. A team of 150+ enthusiastic ProQRians from all walks of life and more than 30 different nationalities is up to this challenge.
Our Axiomer Unit is currently looking for a Program Director Liver (Full-time) to join our team.
As a ProQR Program Director Liver, you will lead research programs in collaboration with internal and external partners focused on the development of novel drug candidates for the treatment of chronic liver diseases. You will be a strong scientific thinker with significant experience leading the discovery and development of oligonucleotide therapies for liver diseases. In your role, you will support, evaluate, and/or identify business development opportunities to enhance project progression and/or platform expansion, with specific application to the needs of the liver portfolio including nucleic acid-based therapeutics and delivery platforms.
How you will contribute:
- Develop and oversee novel scientific projects and manage the work of others directly and in a matrixed structure.
- Lead efforts to determine the mechanism of action for drug targets and candidates using state-of-the-art methods and analytical tools.
- Oversee the execution of drug candidate and platform development programs, utilizing cutting-edge methods and tools such as omics technologies (RNA-seq, proteomics via mass spectrometry), and computational modeling.
- Proactively identify complex obstacles to progress by conducting thorough risk assessments and continuous monitoring of project milestones; recommend and implement innovative solutions.
- Develop and determine optimal methods for new assignments by conducting comprehensive literature reviews, pilot studies, and stakeholder consultations.
- Effectively manage a wide variety of tasks, techniques, and projects by prioritizing workloads and optimizing resource allocation.
- Communicate effectively with colleagues and leadership.
We expect our Program Director Liver to have:
- PhD degree in a scientific discipline with 10+ years of experience in the discovery and development for liver diseases, or
- MS with 14+ years of experience, or
- BS with 16+ years of experience.
- Experience in the field of genetic liver diseases.
- Significant understanding of complex biological systems.
- Expertise in oligonucleotide and/or base editing therapeutics and delivery technologies.
- 10 years of Industry experience required.
- 7 years of Project management experience.
- Experience in supervising/mentoring project teams.
- Proven ability to effectively interact with technical, scientific staff and research management.
- Expertise in the design and execution of in vivo and in vitro studies for the evaluation of liver-related biology and pathology.
- Solid understanding of in silico and computational approaches in drug development.
- The ability to work in a dynamic organization.
Skills and competencies that are required to make a difference:
- Flexible and resistant to change.
- Team player.
- Strong project planning and management skills.
- Critical thinking, decision making and problem-solving skills.
- Pro-active and pragmatic self-starter, with a result-oriented mindset.
ProQR as an employer
As an employer, we are committed to creating an inclusive culture where everyone can be valued for who they are. We offer an exciting and innovative working environment in a very committed organization, with the following benefits:
- An annual performance bonus.
- Stock options.
- A premium-free pension plan.
- A commuting allowance.
- Unlimited (un)healthy snacks and drinks.
- Employee events (boot camp, Rebel Café and other social events).
Do you think you can contribute to achieving our mission? If so, we're looking forward to receiving your application by filling out our application form.
ProQR was founded by Daniel de Boer with a mission to help people living with rare genetic diseases. This remains the sole focus of our company today.
Our passion lies in discovering the latest RNA technologies and translating them to life-changing treatments for people with severe rare and common diseases.
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