Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world's premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: Crinetics Pharmaceuticals is seeking a talented and highly motivated Laboratory Manager to join the drug discovery team. This individual will oversee day-to-day laboratory operations and compound management to support chemistry and biology. Strong laboratory operational knowledge and previous leadership or management experience are highly valued. The Lab Manager will maintain compound management systems, including registering compounds from external sources into the database. The lab manager will also be responsible for developing and managing lab chemical inventory and facilities systems. This position is a unique opportunity to work with a multidisciplinary team in a dynamic company environment in the heart of San Diego's biotechnology community. Essential Job Functions and Responsibilities: These may include but are not limited to: Collaborate with chemists and biologists and assist them with the following:
- Receive and process all compounds from external sources (CRO), including database registration, labeling, delivery/storage to the designated locations, and submission of compounds for internal testing.
- Prepare stock solutions and organize the compound library.
- Prepare compounds and manage shipment for external studies, including weighing, labeling, packaging samples, updating the database, and documenting study requests.
- Receive and process all data from external study vendors, including uploading it to the database.
- Manage chemical inventory, including ordering, entering data into the database, checking in/out chemicals, and dispensing them.
- Manage all laboratory instruments, including calibration and maintenance, service contracts, space allocation, and stock up supplies such as microwave tubes, ISCO columns, LC/MS filters, etc.).
- Maintain laboratory inventory, supply list, and supply stocking.
- Manage all laboratory purchasing, shipping, and receiving.
- Coordinate with IT to manage lab-related hardware, software, and server/system requirements.
- Understand and ensure staff follows industry standards for laboratory compliance and safety.
- Support the organization in maintaining a work environment that fosters learning, open communication, collaboration, and teamwork.
- Additional duties and responsibilities as needed.
Education and Experience: Required:
- Bachelor's Degree in Chemistry or a similar field with 8 years of technical laboratory experience
- 2 years of compound management experience.
- Experience working with compound registration systems such as ChemAxon or CDD vault.
- Willingness to implement laboratory automation to improve workflow and productivity.
- Demonstrated knowledge of federal laboratory compliance standards
- Demonstrated ability to effectively manage time, carrying out different priorities concurrently with the ability to work in a fast-paced environment
- Detail-oriented, with excellent written, communication, organization, and record-keeping skills
- Capable of working both independently and in a collaborative environment
- Personal attributes of integrity, creativity, problem-solving, accountability, and a strong work ethic.
- Software Knowledge: Windows, MS Office
Physical Demands and Work Environment: Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities. Laboratory Activities (if applicable): Biology and chemical laboratory environment experience needed. Environmental health and safety requirements also apply.
Travel: No travel required.
The Anticipated Base Salary Range: $84,000-$112,000 In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process.
Equal Opportunity Employer: Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws.
Vaccination requirement: Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, Crinetics requires that all employees and contractors be fully vaccinated and have received the COVID-19 vaccines as a condition of employment. Full vaccination is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.