Postdoc - Nucleic acids simulation
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Postdoc - Nucleic acids simulation

Rutgers University

Location: Piscataway,NJ, USA

Date: 2024-12-22T08:44:03Z

Job Description:

Position Details

Position Information

Recruitment/Posting Title Postdoc - Nucleic acids simulation Department Proteomics Salary Commensurate With Experience Posting Summary

The Laboratory for Biomolecular Simulation Research ( and Institute for Quantitative Biomedicine ( at Rutgers, the State University of New Jersey, is seeking an application scientist to perform advanced free energy simulations of nucleic acid systems, including but not limited to nucleic acid enzymes and riboswitches. This is an exciting opportunity for a talented scientist to gain valuable experience in using advanced computational methods to tackle high impact problems in enzyme design and drug discovery ( The successful candidate will develop and apply innovative methods and workflows for free energy simulations that leverage new AI-enhanced quantum mechanical force fields to enhanced predictive accuracy. These methods will be integrated into the next-generation Amber software suite used worldwide. In this way, this position provides opportunities to contribute to cutting-edge technology development, including the design of new deep-learning potentials and neural networks that enable fast prediction of nucleic acid targeting small molecules.

Position Status Full Time Posting Number 24FA1324 Posting Open Date 12/13/2024 Posting Close Date 01/31/2025

Qualifications

Minimum Education and Experience

Applicants must hold a PhD in physical chemistry.

Certifications/Licenses Required Knowledge, Skills, and Abilities

Experience in nucleic acid simulations, including modeling of divalent metal ion-nucleic acid interactions and catalysis using combined quantum mechanical/molecular mechanical and free energy path (e.g., finite temperature string) methods. Familiarity with AMBER is strongly encouraged. Strong written and oral communication skills in English are required, as well as the ability to work independently and prepare scientific manuscripts and/or proposals.

Equipment Utilized

Software development will involve computer resources at Rutgers and include access to in-house and national production cyberinfrastructure resources.

Physical Demands and Work Environment

Predominantly operates in an office environment using computer workstation and/or laptop computer, participates in both physical and virtual team meetings, and periodically attends workshops and/or conferences that entail domestic or international travel. Remote work, with regularly scheduled in-person reporting to the PI, is possible through mutual agreement.

Overview

Applicant is expected to perform advanced applications to nucleic acid systems, including free energy simulations using quantum/deep-learning potentials. Duties will involve software development and application, testing and documentation, maintaining currency in the relevant literature and state-of-the-art technology, and actively engage in a team environment.

Statement

Posting Details

Special Instructions to Applicants

Please provide the documents listed below (cover letter, CV, two references)

Quick Link to Posting Campus Rutgers University-New Brunswick Home Location Campus Busch (RU-New Brunswick) City Piscataway State NJ Location Details

Pre-employment Screenings

All offers of employment are contingent upon successful completion of all pre-employment screenings.

Immunization Requirements

Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.

Affirmative Action/Equal Employment Opportunity Statement

It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address:

Posting Specific Questions

Required fields are indicated with an asterisk (*).

Applicant Documents

Required Documents

* Resume/CV

* Cover Letter/Letter of Application

* Curriculum Vitae

* List of Professional References (contact Info)

Optional Documents

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