Contractor Protein Sciences – Research Scientist/Senior Research Scientist
Vertex Pharmaceuticals is seeking a highly motivated scientist with expertise in Protein Expression and Purification, and a track record of generating high-quality recombinant protein for biochemistry, biophysics and structural biology experiments.
Key Responsibilities:
- Expression, purification, and characterization of mammalian integral membrane proteins for assay development and biophysical experiments.
- Design and implement protein purification protocols to generate high quality, homogeneous protein, using various chromatography methods such as affinity, size exclusion, ion exchange.
- Proactively troubleshoot the expression and purification of challenging targets to ensure consistent deliveries of high-quality protein.
- Characterization of the stability and homogeneity of purified proteins using techniques such as FPLC, HPLC, SDS-PAGE, LC-MS.
- An open mindset and willingness to learn new techniques as needed to support the Protein Sciences group is desirable.
Requirements:
- Minimum requirement is Bachelor's degree and 2 years' experience in a research laboratory. Post-graduate degree in Biochemistry, Molecular Biology, or a related field, and /or industry experience is a plus.
- Proven record and expertise in molecular biology and protein chemistry techniques. Experience in membrane protein purification, and CryoEM sample preparation is a plus.
- Team oriented, with the ability to work effectively in a fast-paced, timeline-driven work environment.
- Excellent organizational and documentational practices.
Pay Range:
$50 - $60/HR
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