Research Associate II-Bench
: Job Details :

Associate II-BenchSeattle, Washington I Research | Full time @ 40 Hours/Week | Regular & Day Shift | R242472SUMMARY OF POSITION:Dr. Mara Pavel-Dinu's laboratory seeks a Research Associate-I with the dual function of Laboratory and Mouse Colony Manager to support a newly opened and growing lab. The position offers the opportunity to provide the PI and the research team with organizational and technical support and engage in high-impact research. You will be part of a highly interactive, supportive, and inclusive research group expanding upon our genome editing platform for advancing novel treatments for patients with inherited immune disorders (PMID: 38096800, PMID: 30967552, PMID:33712802, PMID: 35773054). The newly established research group is part of the Center of Immunity and Immunotherapies (CIIT) of Seattle Children's Research Institute (SCRI). Seattle Children's Research Institute and Pavel-Dinu Laboratory offer competitive salaries, a Seattle area cost-of-living bonus, and a generous benefits package as a full-time employee.JOB RESPONSIBILITIES:The ideal candidate will divide their time between lab and mouse colony management and research. The percent effort may change according to research needs and publication or grant deadlines.Lab Management (~35%) - Responsible for helping oversee the day-to-day operational needs of the laboratory. This includes but is not limited to:

• The organization of laboratory materials, space, personnel, and equipment to ensure a clean and efficient environment for conducting cutting-edge research.
• Order and receive supplies, oversee equipment maintenance contracts, work with vendors for equipment repair and purchase, and manage overall lab organization.
• Perform all regulatory procedures for the lab, including writing and maintaining regulatory applications such as animal use protocols (IACUC) and IBC protocol, chemical database, managing the approval process, ensuring personnel training, and organizing the inspections for the various regulatory agencies.

Mouse Colony Manage (~ 35%) - Responsible for managing a mid-size mouse colony together with the Pl and researchers. This includes but is not limited to:

• Setting up breeding and working with the on-site veterinary personnel to ensure the health of the colony
• Performing genotyping and various techniques: collecting blood, mice irradiation pre-transplant, intra-femoral/intra-hepatic/intra-venous transplantation assays, monitoring health post-transplant,
• Help perform end-point transplant assays: harvesting and processing samples for downstream analyses. Training will be provided when necessary.

Research (~30%) - Responsible for executing and interpreting experiments under the PI's direct guidance.

• Depending on the candidate's training and interest, the candidate will be offered a research project involving developing or optimizing in vitro assays and/ or in vivo models to evaluate cellular products
• Present data at internal and external meetings and contribute data to manuscript publications.

Required Education and ExperienceBachelor's Degree in Microbiology, Biochemistry, Immunology, or related field.At least five (5) years laboratory experience.Required CredentialsN/A.Preferred- Knowledge of murine model systems and experience handling mice OR comfortable and willing to learn these techniques- Understanding of academic research facility needs- General background in a discipline related to specific lab(s) work- Demonstrated supervisory experience- Knowledge and experience in managing facilities, operations, maintenance, space, and equipment administration in a research or teaching setting.- Experience with maintaining mouse colony: breeding, genotyping, keeping clear and up-to-date records of the mouse colony, monitoring the overall well-being of the colony- Expertise in mouse-handling techniques- Experience with cell culture techniques, molecular biology, and/or animal modelsCompensation Range$28.44 - $42.66 per hourSalary InformationThis compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.Disclaimer for Out of State ApplicantsThis compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factorsBenefits InformationSeattle Children's offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits.About UsHope. Care. Cure. These three simple words capture what we do at Seattle Children's - to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECUREOur founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families' ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho - the largest region of any children's hospital in the country. In 2022, U.S. News & World Report once again ranked Seattle Children's among the nation's best children's hospitals - for the 30th year in a row. For more than a decade, Seattle Children's has been nationally ranked in all 10 specialty areas evaluated by U.S. News & World Report. We are honored to be the top-ranked pediatric hospital in Washington and the Pacific Northwest. As a Magnet designated institution, and classified among America's best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it's delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.Our Commitment to DiversityOur community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.The people who work at Seattle Children's are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.Seattle Children's is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.