Location: Ann Arbor,MI, USA
How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Job Summary
The microbiome represents an exciting frontier in medicine, and early successes in the field have demonstrated the dynamic interactions among individual microbial species and highlighted the crosstalk between microbiota and their hosts at the mucosal interface. The Li research group has been focusing on the development of molecular and live cell-based therapeutics, with a major emphasis on harnessing innovative synthetic biology, microbial engineering, and drug delivery approaches for improving human health in a sustainable manner. Currently, three directions are being explored: (1) engineering probiotics to secrete biologics such as nanobodies to address intestinal diseases; (2) understanding the interactions between oral microbiota and the host; and (3) engineering probiotics for cancer immunotherapy. These efforts are supported by internal and extramural funding sources.
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
* Excellent medical, dental and vision coverage effective on your very first day
* 2:1 Match on retirement savings
Responsibilities*
* Communicate with vendors on purchasing instruments.
* Facilitate day-to-day research laboratory operations, including procurement and inventory of reagents and supplies.
* Manage the laboratory's IBC protocol to ensure safe usage of recombinant DNA constructs, viral gene delivery systems, and human cell cultures.
* Manage multiple IACUC protocols (involving rodents) and serve as the point of contact for biannual IACUC inspections.
* Serve as the laboratory's safety officer, maintaining all required documentation for annual EHS inspections.
* Provide technical support to a range of research projects using various techniques including bacterial and mammalian cell culture, recombinant DNA techniques, and qPCR.
* Facilitate animal research by the faculty, students, and postdocs in the lab by assisting with animal surgeries and post-surgical care.
Required Qualifications*
* This position requires a BS or MS, preferably in microbiology, molecular biology, bioengineering, chemistry, or related discipline preferred.
* 1 to 3 years related experience.
* Candidates must be interested in working with technical aspects of cancer/rare disease diagnosis/therapy and their translations to clinical applications.
* Familiar with the operation and performance of basic lab equipment, i.e., centrifuge, microscopes, etc.
* Good organizational skills and abilities to work alongside other scientists without extensive supervision are also required. Willingness to learn new techniques as required for project progress.
Desired Qualifications*
* Familiarity with molecular cloning, flow cytometry, immunoassays, cell and organoid culture is preferred.
* Experience of animal models is strongly preferred.
* 1-2 years of prior research experience is preferred, but not required.
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes