Location: Ann Arbor,MI, USA
How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Job Summary
The West Laboratory at the University of Michigan in Ann Arbor is seeking a Research Laboratory Tech Lead. Research in the West Lab focuses on breast cancer tumor progression and metastasis. We are focused on understanding how epithelial tissue becomes broken down to facilitate aggressive cancer cell behaviors. We combine mouse models of breast cancer, organoids, 3D cell and tissue culture, advanced microscopy techniques, and transcriptomic analyses with conventional cell and molecular biology approaches to reveal mechanisms underlying tumor progression and metastasis.
Mission Statement
The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future.
Why Work at Michigan?
In addition to a career filled with purpose and opportunity, The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family and plan for a secure future. Benefits include:
* Generous time off
* A retirement plan that provides two-for-one matching contributions with immediate vesting
* Many choices for comprehensive health insurance, including dental/vision
* Life insurance
* Maternity/Parental Leave
* Long-term disability coverage
* Flexible spending accounts for healthcare and dependent care expenses
Responsibilities*
Research Development and Execution: (70%)
* Maintain mouse colony. This includes working hands-on with mice to perform genotyping, breeding/weaning, tumor monitoring, and maintaining an up-to-date census. The candidate will work with lab members to decide which mice will be required for upcoming experiments in the lab and manage the number of mice in the colony to reflect these needs. The candidate will also oversee all animal experiments in the lab, ensuring all approved IACUC protocols and best practices are being followed, and deciding when lab members have adequate training to perform experiments in mice (i.e. survival surgeries, etc). (50%)
* Design research methods for cell and molecular biology experiments related to the lab's research interests as well as executing research plans and analysis of results, including tissue culture, PCR, gel electrophoresis, DNA and RNA sequencing, DNA/RNA/Protein extractions, Western Blots, proteomic approaches (Mass spectrometry), microscopy, cell/tissue processing and microscopy, cloning (Gibson and restriction enzyme based. This includes taking primary responsibility for some experiments and parts of larger projects. The candidate will decide which project within the lab's research portfolio fits their interests and decide which experiments to perform for their project. (20%)
Lab Management and Supervision (30%)
* Supervise and train lab members (Graduate Students, undergraduate students, Post Docs, other lab staff) in the core experimental and data analysis techniques used in the lab and work with mice. (11%)
* Deciding which supplies are best for the lab, ordering said supplies, and maintaining the budget line items. (8%)
* Ensure our lab is operating effectively. (3%)
* Oversee equipment purchases, repairs, and maintenance. (2%)
* Designing standard operating procedures that comply with lab safety protocols. (2%)
* Perform administrative work. (1%)
* Participate in the preparation of research proposals and manuscripts for publication. (3%)
Required Qualifications*
Candidate must have a Bachelor's degree in related field. 2-3 years of related experience
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes