Scientist
: Job Details :

Title: Scientist II

Responsibilities:

• mRNA platform site
• cell based screenings
• goes to different functional groups for testing
• some background in nucleic acids – mRNA technology
• invitro transcription
• basic understanding of chemistry
• purification strategies for mRNA
• ELISA, PCR
• AKTA – preferred

MUST HAVE:

• RNA biochemistry
• understanding of nucleic acid
• molecular biology

Day to Day:

• planning experiments
• invitro transcriptions
• QCs
• molecular biology work – cell testing of generated mRNAs

Key Responsibilities:

· In vitro transcription to produce mRNA at different scales to support the platform development and therapeutic programs.

· RNA Purification using affinity chromatography (AKTA) and other strategies for purification.

· Quality control assays for mRNAs like electrophoresis, ELISA, qPCR, etc.

· Perform cell-based assays, such as cell culture, transfection, and flow cytometry.

· Work closely with the manager and cross-functional team members on multiple tasks with the ability to analyze, interpret, and present data.

· Assist in ordering reagents from internal and external suppliers and communicating with CROs.

· Generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments. Demonstrate broad and versatile technical expertise within discipline.

· Maintain electronic laboratory notebooks (ELN) in compliance with the Company Laboratory Notebook Policy.

· Stay updated and in compliance on all departmental and corporate training.

Key Qualifications:

· MS in molecular biology, biochemistry, biomedical engineering or related field with 0-2 years of experience in biotherapeutics or genetic medicine or BS with a minimum of 3-5 years of relevant industry experience.

· Hands-on experience with nucleic acid preparation, purification (AKTA), QC, and cell-based assays.

· Working knowledge of related tools/software (SnapGene, Prism, FlowJo, Excel, PowerPoint etc.).

· Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment with demonstrated problem-solving skills.

· High-quality written and oral communication skills and the ability to excel in a collaborative environment.