Location: Manchester,NH, USA
California, US residents click here.
The job details are as follows:
What We Do
We build on the strength of our research and development expertise and a distinctive, entrepreneurial culture that encourages diversity, innovation, creativity, sustainability, and, simply, fun. Since inception, our mission has been to find a cure for pulmonary arterial hypertension and other life-threatening diseases. Toward this goal we have successfully gained FDA approval for five medicines, we are always conducting new clinical trials, and we are working to create an unlimited supply of manufactured organs for transplantation.
We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation (PBC). Our public benefit purpose is to provide a brighter future for patients through (a) the development of novel pharmaceutical therapies; and (b) technologies that expand the availability of transplantable organs. At the same time, we seek to provide our shareholders with superior financial performance and our communities with earth-sensitive energy utilization.
Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of medicines for life . We continue to research and develop treatments for cardiovascular and pulmonary diseases, and other orphan diseases.
How you'll contribute
The Senior Scientist, Cell Production & Analytical Development (OMG) will design and lead efforts in developing and implementing robust analytical methods for the assessment of somatic cells and differentiation of iPS-derived cells for development of autologous 3D printed tissue engineered organs. The incumbent and team will also be tasked with providing rapid turn-around testing results to further process development efforts in achieving high quality and highly suitable cellular products for long-term cellularized 3D scaffolds and development of autologous 3D printed tissue engineered organs.
* Design and lead complex projects including the development, execution and troubleshooting of various analytical techniques relevant to the assessment of iPS-derived cells and their subsequent performance on cellularized 3D scaffolds
* Assist in execution of short- and mid- term planning of analytical activities to support department and site goals
* Design and lead the development and implementation of analytic methods to characterize quality and suitability of iPS-derived cells for generation of 3D printed organs
* Design and execute laboratory experiments that lead to the successful achievement of program objectives
* Foster and leverage synergistic interactions with other sub-groups in Organ Manufacturing (e.g., Bioink, Scaffold Production, Cellularization), as needed
* Participate in selection, purchase, and implementation of laboratory equipment
* Develop, write and review laboratory methods, protocols, development reports.
* Lead effective tech transfer activities from outside collaborators to internal laboratory
* Design the evaluation of new technologies for future analytical development and suitability of assays in overall testing schema.
* Interact with R&D and QC teams to ensure process and methods for assessment of iPS-derived cells are ready and phase-appropriate
* Author and contribute to scientific publications and present data at scientific conferences
* Author and contribute to IP and regulatory filings
* Perform all other duties as assigned
For this role you will need
Minimum Requirements for Scientist:
* Doctor of Philosophy (PhD) in biomedical engineering, cell biology, molecular biology, or other related discipline
* 2+ years of relevant experience that can include experience in stem cell differentiation or reprogramming or bioreactor cell production scale up or regenerative medicine or tissue engineering
* Technical expertise in iPS-reprogramming and/or differentiation methods
* Ability to initiate and manage day-to-day-tasks effectively, including multi-tasking, flexibility, adaptability, and high quality rapid turn-around of data
* Faculty with appropriate word processing, spreadsheet, presentation and related standard software; experience with laboratory instrumentation and data software
Minimum Requirements for Senior Scientist:
* Doctor of Philosophy (PhD) in biomedical engineering, cell biology, molecular biology, or other related discipline
* 5+ years of relevant experience that can include experience in stem cell differentiation or molecular biology or analytical development or regenerative medicine or tissue engineering
* Technical expertise in molecular techniques applicable to iPS-reprogramming and/or differentiation methods,
* Ability to initiate and manage day-to-day-tasks effectively, including multi-tasking, flexibility, adaptability, and high quality rapid turn-around of data
* Knowledge in transfer of Analytical Development methods to QC, or tech transfer experience
* Faculty with appropriate word processing, spreadsheet, presentation and related standard software; Experience with laboratory instrumentation and data software
* Ability to mentor and motivate team members
Preferred Qualifications for Scientist:
* Technical expertise in iPS-derived cell types, including knowledge of cell biology stress cues
* Ability to mentor and motivate team members
* Knowledge in transfer of Analytical Development methods to QC
Preferred Qualifications for Senior Scientist:
* Technical expertise in iPS-derived cell types, including knowledge of cell biology stress cues
At United Therapeutics, you'll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged... all while making a difference in the lives of our patients.
Eligible employees may participate in the Company's comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit
While United Therapeutics does not require vaccination for Covid-19 at this time, we strongly encourage all employees and visitors to remain up to date on vaccinations and boosters to protect one another from illness. Employees working in customer-facing roles must adhere and comply with customers' credentialing guidelines, which may require vaccination against Covid -19, the influenza virus, and other illnesses that could be harmful to healthcare staff and patients.
United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities