We are LOTTE BIOLOGICS! Delivering Therapies That Enable a Healthier World. A new company, built on 80 years of tradition. We embody our core values of being Inspired by Science, Embracing Diversity, Fostering Talent, and Connecting Lives. Our mission is to be the most trusted partner in the industry, with high standards of quality and continuous innovation, to reliably deliver benefits for patients worldwide. Position SummaryThe Senior Manager, Downstream Process Development leads the Downstream Development Labs and oversees all data and documentation related to product purification of biopharmaceutical products. The Senior Manager drives departmental and company goals, milestones, and innovation to completion.Duties & Responsibilities
- Drives the completion of financial business drivers (milestones, revenue generation, innovation).
- Contributes to the design of the company strategy and vision.
- Leads by example and with empathy
- Establishes good working relationships with peers and other colleagues as a team player and collaborator.
- Stays current with all training requirements.
- Follows procedures to ensure a safe working environment including but not limited to reporting safety incidents.
- Communicates with peers and other colleagues concisely and efficiently.
- Displays initiative for continuous improvement, learning new techniques, and maintaining the lab.
- Able to problem solve and critically think through processes
- Client oriented with excellent time management skills able to multitask, meet deadlines, and prioritize activities
- Executes assignments independently.
- Leads and builds a department comprised of scientist and associate teams.
- Facilitates and leads training of new employees
- Displays a positive attitude and good change readiness.
- Ability to provide technical support through troubleshooting, problem solving and collaboration.
- Able to interpret data and design subsequent experiments.
Education & Experience
- One of the following must be met:
- Bachelor's degree in life science with 9-11 years of direct related experience.
- Master's degree in life science with 6-9 years of direct related experience.
- PhD in life science with 4-6 years of direct related experience.
- Managerial experience of ?5 years managing a team of associates is preferred.
- Must be able to work full-time and the occasional nights and weekends
Knowledge, Skills, Abilities
- Strong knowledge of biochemistry, chemistry, and protein expression
- Expertise in concepts and performance of routine wet lab chemistry (preparation of buffers and solutions, use of balances, chemical formulation preparation/mathematics, etc.)
- Expertise in concepts and execution of protein isolation including centrifugation, cell disruption, chromatography, dead-end and tangential flow filtration
- Proficiency in understanding and use of Unicorn software including method design
- General knowledge of common protein analytical techniques such as spectrophotometry, SDS-PAGE, SE-HLPC, RP-HPLC, ELISA, etc
- General knowledge of mammalian cell growth and bioprocessing
- Understanding of concepts and execution of Design of Experiment (DoE) studies, Quality by Design (QbD), Failure Modes Effects Analysis (FMEA), JMP software, and the application of statistical modeling in process development and process characterization
- General knowledge of tech transfer processes and scale-up techniques
- Effectively conveys complex scientific concepts and models effective scientific communication to team members and industry colleagues by authoring publications and presenting at industry conferences or webinars
- Good knowledge of GLP, GMP, and regulatory guidance for biopharmaceuticals
- Proficient computer skills (e.g., Microsoft Office, Excel, Word, PowerPoint)
- Prepares data summaries, reports and process descriptions for process development activities.
- Develops training plans for scientists to develop in technical and leadership skills.
- Maintains detailed and accurate records by logging equipment usage, procedures and results in logbooks, Batch Records, or laboratory notebooks in accordance with GDPs.
- Actively participates in and troubleshoots general laboratory maintenance (e.g., material ordering, inventory management, record management, general housekeeping, equipment).
Physical Demands
- Appropriate levels of personal protective equipment (PPE) is required for this position.
- Frequent repeated motions such as grasping, fine manipulation, lifting, bending, twisting, squatting, crouching, kneeling, sitting, crawling, reaching, climbing on step stools, and reaching is required. Repetitive use of arms/hands/wrists and visual acurity is required. This role may also require unassisted lifting (not to exceed 50 lbs).
- Dynamic, fast-paced, interactive, and entrepreneurial environment
Work Environment
- The position is based indoors, and the individual will primarily be working with others, but also independently. This position will work in both an office space and lab space.
- The position is a team and project-based position that will require occasional shift work, weekends, evenings, and holidays.
- This role may be exposed to dust, mist, fumes, chemicals and allergens.
Supervisory Responsibilities This position is a direct people manager responsible for:
- Driving the completion of financial business drivers (milestones, revenue generation, innovation).
- Contributing to the design of the company strategy and vision.
- Leading and building a department comprised of scientist and associate teams.
- Facilitating and leading training of new employees
TravelThis position requires up to 10% of travel.Target Bonus16%New York Pay Range$91,000-$142,000 USDWork LocationEast Syracuse, NY We are an Equal Employment Opportunity ( EEO ) Employer. We believe that women, people of color, veterans and LGBTQ communities must participate in the work we do, so we strongly encourage applications from people with these identities or who are members of underrepresented communities! If this is the work that you want to do, in a culture of inclusion and excellence with the goal of making our world to be a healthier place, then please apply today!