Director, Preclinical Pharmacology (RNA/Oligo)
Location: New England/Remote
HireMinds is representing a client specializing in the siRNA, RNAi, & Oligonucleotide space that is using AI platform for the discovery of novel therapeutics. We are seeking to add your expertise in leading IND-enabling programs for this team. As the Director of Preclinical Development, you'll lead a team in the design and execution of in vivo pharmacology and preclinical projects. Reporting to the Vice President, you'll provide scientific and technical leadership to a team of 3 reports, ensuring projects meet strategic goals and regulatory standards. You'll develop timelines and ensure studies, data, and findings are reported in an efficient manner and under regulated standards in this exciting leadership role. Please reach out to the HireMinds team or apply today!
You Will Be Responsible For:
- Effectively managing a team of 3 direct reports (1 Associate Director, 2 Sr. Scientists) in preclinical development function.
- Leading cross-functional teams in developing an in vivo strategy for efficient decision-making across the organization.
- Design preclinical programs with clear milestones, ensuring timelines are met.
- Present project updates to the Executive Team and collaborate with internal stakeholders.
- Manage partnerships with CROs to support data generation and regulatory needs.
- Serve as an expert in targeted liver disease areas, adapting strategies based on competitive landscapes.
- Develop Target Validation and refine biological readouts based on data insights.
You Will Bring With You:
- PhD in biology, pharmacology, or related field, with expertise in translating in vivo models to human diseases.
- 10+ years' experience in drug discovery within pharma or biotech, focusing on in vivo pharmacology and preclinical models to progress successful drug candidate evaluations.
- Proven ability to identify and validate in vivo models across disease areas including: liver disease, blood disorders, ocular, and cardiovascular models.
- Experience in managing CROs partnerships successfully throughout your career.
- Commitment to ethical standards and regulatory compliance in data generation and study conduct.
- Project management and leadership skills leading to successfully achieving project milestones.
- Excellent communication skills in scientific reporting and regulatory documentation.
- Proven success and experience with IND-enabling activities and regulatory submissions.
- Experience with modalities including: siRNA, RNAi, RNA or oligonucleotide therapeutics.