Sr. Research Associate, in vivo Pharmacology
: Job Details :

Sr. Research Associate, in vivo Pharmacology

About Firefly Bio:

Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with cell-type selective protein degraders. Our mission is to unlock the full potential of bioconjugates and develop medicines with long-lasting benefits for patients. We are establishing an expert team to build state-of-the-art platform capabilities for the discovery and development of innovative drug conjugates. Our company culture is built on the values of Focus, Integrity, Respect and Energy. We are looking for enthusiastic individuals committed to making an impact on the future of medicine.

Position Summary:

We are seeking a highly motivated Research Associate to join our in vivo pharmacology team with a focus on oncology. The selected candidate will be responsible for evaluating novel ADC based oncology therapeutics in pre-clinical models. Hands on experience and knowledge of mouse oncology models and cancer biology are required. The successful candidate will be responsible for executing and communicating in vivo data to support the progression of oncology focused programs. Title and compensation will be commensurate with experience.

Primary Responsibilities:

• Plan and execute, troubleshoot and analyze in vivo pharmacology experiments (efficacy CDX models, PK/PD)
• Perform cell culture, tumor inoculation, therapeutic dosing, tumor measurements and collecting tissues from rodent in vivo studies.
• Contribute to pre-clinical model development, optimization and characterization
• Adhere to proper animal handling and ethical standards, ensuring all procedures are performed according to established guidelines.
• Interface with cross-functional project team members, and participate in and present at project team meetings and cross-departmental team meetings

Qualifications & Prior Experience required:

• BS or MS in Biology, Pharmacology or a related discipline
• >4 years of hands-on in vivo model research experience in an industry setting
• Must have a strong work ethic and be enthusiastic about animal and laboratory work
• Expertise with mouse models of human cancer
• Proficiency with various mouse handling techniques including dosing (IV, PO, subcutaneous, IP), tumor inoculation/measurements, in life and terminal blood collection, collection and handling of tissues during necropsy and processing for ex vivo analysis
• Experience with sterile tissue culture, and molecular and basic cellular biology techniques
• Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word
• Excellent organizational and communication skills, along with the ability to work effectively in a multidisciplinary team environment
• Perform timely data verification and ensure accuracy for laboratory notebooks, protocols and reports
• Demonstrated ability to work independently on day-to-day responsibilities and research goals
• Must be detail-oriented, punctual, reliable and available on weekends when necessary
• Ability to work in a fast-paced environment and adapt to change

Benefits:

Every team member is essential in shaping Firefly Bio's culture and science and for our success. We offer competitive compensation packages including stock options and the opportunity to be part of ground-breaking research. Firefly Bio is an equal opportunity employer and will consider all applicants for employment. Firefly Bio does not discriminate on the basis of race, sex, color, religion, age, national origin, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits.