Location: Tarrytown,NY, USA
Worldwide more than 1 billion people have obesity, and the global market for Obesity-related therapeutics is expected to exceed $100B. Regeneron's lead program (anti-myostatin) addressing the quality of weight reduction is entering late-stage development and has the potential to have profound impact on patients' lives. Regeneron also has a deep pipeline with additional Obesity- and metabolism-related candidates with potential to transform care. To take full advantage of these opportunities, Regeneron will have to execute clinical development and commercial launch for the Obesity franchise at a scale and pace unprecedented at Regeneron in a highly competitive field.
The Global Program Head (GPH) - Obesity & Metabolism, will play an integral role in successful late-stage development, global launch, and lifecycle management of our initial programs in Regeneron's Obesity franchise. Partnering with Senior leadership and other CVRM GPHs to execute the portfolio, the GPH will lead the late-stage development, strategy, and execution for our lead programs while advising on combinations, sequencing, and integrated portfolio strategy for Regeneron's rapidly progressing pipeline. This role requires expertise in obesity and metabolic disorders management, a track record of successful drug development, as well as strong ability to lead cross-functional teams representing almost all areas within the company, including research, non-clinical development, clinical development, regulatory, CMC, medical safety, medical affairs, commercial, finance, legal, BD and alliance management. In partnership with the Program Manager, the GPH is accountable for ensuring operational execution of all phases of development, proactively identifying and mitigating risks, and meeting regulatory milestones. The successful candidate will have a strong ability to define and translate a scientific narrative, extensive experience in overseeing large-scale, complex late-stage programs, and a record of accomplishment of devising innovative development and go-to-market strategies with a patient-centric focus.
Key Responsibilities:
* Strategic Leadership and Program Development
* Build and lead Strategic Program Teams (SPT) to develop long-term, integrated program strategies, target product profiles, and scientific narrative. The GPH is expected to be both advocate and critic of the program and its future development within Regeneron.
* Align and drive broader cross-functional perspective in developing program strategies including scientific rationale, operational feasibility, budget, timeline, in the context of the competitive and commercial landscape.
* Ensure scientific rigor and innovation drive the program strategy.
* Provide feedback on functional strategies including research, clinical, regulatory, supply, and commercial.
* Proactively identify new opportunities.
* Proactively identifies risks and oversees assessment and mitigation activities.
* Program Execution and Governance
* Accountable for the quality and execution of SPT deliverables, milestones, and governance interactions.
* Oversee and hold sub-teams and their leads accountable for executing the program strategy, development plan, and timelines.
* Coordinate the program's progression at key transition points (e.g., submission/launch).
* Maintain a full financial perspective of the program budget and future development costs, and actively manage the financial resources of the program.
* Stakeholder Engagement and Communication
* Identify and align with key stakeholders across Regeneron and partners, ensuring engagement throughout the program lifecycle.
* Prepare team for governance interactions
* Prepare and lead SPT meetings, ensuring effective decision-making and communication of key decisions and developments.
* Able to effectively represent the program and Regeneron externally, as well as prepare and coach the team on external representation.
* Represent Regeneron at joint development committees (where applicable).
* Team Development and Coaching
* Support the professional development of SPT members.
* Promote a culture of scientific rigorous and innovative thinking on the team.
* Coach the team to success.
Requirements:
* 10 years minimum experience with broad drug development experience
* MD, PhD, PharmD
* Proven leadership in advancing programs through development milestones, approval, and launch in biotechnology/pharmaceutical companies
* Deep expertise in clinical development, especially in obesity/cardiometabolic fields; biologics development experience is a plus.
* Expert knowledge of the competitive landscape and regulatory requirements for drug approval in the obesity/cardiometabolic space.
* Proven ability to build and lead cross-functional teams, map out deliverables, and ensure program progress.
* Ability to design, convey, and implement development strategies, anticipate risks, and develop mitigation strategies.
* Experience working in a highly matrixed environment and influencing across functional areas.
* Ability to rigorously interpret and pressure test various types of data (clinical, preclinical, operational).
* Strong analytical abilities and critical thinking skills, capable of presenting to senior management.
* Excellent communication skills for reporting plans, options, and outcomes to management, driving decision-making, and translating across functions to build alignment.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually)
$300,000.00 - $500,000.00